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Celecoxib reduces hepatic vascular resistance in portal hypertension by amelioration of endothelial oxidative stress

The balance between endothelial nitric oxide (NO) synthase (eNOS) activation and production of reactive oxygen species (ROS) is very important for NO homeostasis in liver sinusoidal endothelial cells (LSECs). Overexpression of cyclooxygenase‐2 (COX‐2), a major intravascular source of ROS production,...

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Detalles Bibliográficos
Autores principales: Tai, Yang, Zhao, Chong, Zhang, Linhao, Tang, Shihang, Jia, Xintong, Tong, Huan, Liu, Rui, Tang, Chengwei, Gao, Jinhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581330/
https://www.ncbi.nlm.nih.gov/pubmed/34609050
http://dx.doi.org/10.1111/jcmm.16968