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ERK5 signalling pathway is a novel target of sorafenib: Implication in EGF biology

Sorafenib is a multikinase inhibitor widely used in cancer therapy with an antitumour effect related to biological processes as proliferation, migration or invasion, among others. Initially designed as a Raf inhibitor, Sorafenib was later shown to also block key molecules in tumour progression such...

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Detalles Bibliográficos
Autores principales: Ortega‐Muelas, Marta, Roche, Olga, Fernández‐Aroca, Diego M., Encinar, José A., Albandea‐Rodríguez, David, Arconada‐Luque, Elena, Pascual‐Serra, Raquel, Muñoz, Ismael, Sánchez‐Pérez, Isabel, Belandia, Borja, Ruiz‐Hidalgo, María J., Sánchez‐Prieto, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581332/
https://www.ncbi.nlm.nih.gov/pubmed/34655447
http://dx.doi.org/10.1111/jcmm.16990