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HIF‐1α promotes the proliferation and migration of pulmonary arterial smooth muscle cells via activation of Cx43

The proliferation of pulmonary artery smooth muscle cells (PASMCs) is an important cause of pulmonary vascular remodelling in hypoxia‐induced pulmonary hypertension (HPH). However, its underlying mechanism has not been well elucidated. Connexin 43 (Cx43) plays crucial roles in vascular smooth muscle...

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Detalles Bibliográficos
Autores principales: Han, Xiao‐Jian, Zhang, Wei‐Fang, Wang, Qin, Li, Min, Zhang, Chun‐Bo, Yang, Zhang‐Jian, Tan, Ren‐Jie, Gan, Li‐Jun, Zhang, Le‐Ling, Lan, Xue‐Mei, Zhang, Fang‐Lin, Hong, Tao, Jiang, Li‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581339/
https://www.ncbi.nlm.nih.gov/pubmed/34698450
http://dx.doi.org/10.1111/jcmm.17003