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Highly Purified Alloantigen-Specific Tregs From Healthy and Chronic Kidney Disease Patients Can Be Long-Term Expanded, Maintaining a Suppressive Phenotype and Function in the Presence of Inflammatory Cytokines

The adoptive transfer of alloantigen-specific regulatory T cells ((allo)Tregs) has been proposed as a therapeutic alternative in kidney transplant recipients to the use of lifelong immunosuppressive drugs that cause serious side effects. However, the clinical application of (allo)Tregs has been limi...

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Detalles Bibliográficos
Autores principales: Cortés-Hernández, Arimelek, Alvarez-Salazar, Evelyn Katy, Arteaga-Cruz, Saúl, Rosas-Cortina, Katya, Linares, Nadyeli, Alberú Gómez, Josefina M., Soldevila, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581357/
https://www.ncbi.nlm.nih.gov/pubmed/34777330
http://dx.doi.org/10.3389/fimmu.2021.686530