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Highly Purified Alloantigen-Specific Tregs From Healthy and Chronic Kidney Disease Patients Can Be Long-Term Expanded, Maintaining a Suppressive Phenotype and Function in the Presence of Inflammatory Cytokines
The adoptive transfer of alloantigen-specific regulatory T cells ((allo)Tregs) has been proposed as a therapeutic alternative in kidney transplant recipients to the use of lifelong immunosuppressive drugs that cause serious side effects. However, the clinical application of (allo)Tregs has been limi...
Autores principales: | Cortés-Hernández, Arimelek, Alvarez-Salazar, Evelyn Katy, Arteaga-Cruz, Saúl, Rosas-Cortina, Katya, Linares, Nadyeli, Alberú Gómez, Josefina M., Soldevila, Gloria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581357/ https://www.ncbi.nlm.nih.gov/pubmed/34777330 http://dx.doi.org/10.3389/fimmu.2021.686530 |
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