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Interleukin-24 inhibits the phenotype and tumorigenicity of cancer stem cell in osteosarcoma via downregulation Notch and Wnt/β-catenin signaling

Osteosarcoma frequently presents as recurrence and metastasis, even if the primary lesion was eradicated and/or radiotherapy and chemotherapy were administered. Osteosarcoma cancer stem cells (CSCs) are one of the key factors for the recurrence and metastasis of osteosarcoma. We have shown that inte...

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Detalles Bibliográficos
Autores principales: Zhuo, Baobiao, Wang, Xihua, Shen, Yang, Li, Jiayong, Li, Shixian, Li, Yuan, Wang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581362/
https://www.ncbi.nlm.nih.gov/pubmed/34804789
http://dx.doi.org/10.1016/j.jbo.2021.100403