Cardiac Fibroblast Growth Factor 23 Excess Does Not Induce Left Ventricular Hypertrophy in Healthy Mice

Fibroblast growth factor (FGF) 23 is elevated in chronic kidney disease (CKD) to maintain phosphate homeostasis. FGF23 is associated with left ventricular hypertrophy (LVH) in CKD and induces LVH via klotho-independent FGFR4-mediated activation of calcineurin/nuclear factor of activated T cells (NFA...

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Detalles Bibliográficos
Autores principales: Leifheit-Nestler, Maren, Wagner, Miriam A., Richter, Beatrice, Piepert, Corinna, Eitner, Fiona, Böckmann, Ineke, Vogt, Isabel, Grund, Andrea, Hille, Susanne S., Foinquinos, Ariana, Zimmer, Karina, Thum, Thomas, Müller, Oliver J., Haffner, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581397/
https://www.ncbi.nlm.nih.gov/pubmed/34778257
http://dx.doi.org/10.3389/fcell.2021.745892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581397/
https://www.ncbi.nlm.nih.gov/pubmed/34778257
http://dx.doi.org/10.3389/fcell.2021.745892

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