UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus

Activation-induced deaminase (AID) is the major actor of immunoglobulin (Ig) gene diversification in germinal center B-cells. From its first description, it was considered as mandatory for class switch recombination (CSR), and this discovery initiated a long quest for all of the AID-interacting fact...

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Detalles Bibliográficos
Autores principales: Dalloul, Iman, Laffleur, Brice, Dalloul, Zeinab, Wehbi, Batoul, Jouan, Florence, Brauge, Baptiste, Derouault, Paco, Moreau, Jeanne, Kracker, Sven, Fischer, Alain, Durandy, Anne, Le Noir, Sandrine, Cogné, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581400/
https://www.ncbi.nlm.nih.gov/pubmed/34777346
http://dx.doi.org/10.3389/fimmu.2021.737427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581400/
https://www.ncbi.nlm.nih.gov/pubmed/34777346
http://dx.doi.org/10.3389/fimmu.2021.737427

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