Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury

Background: Microglia and macrophages adopt a pro-inflammatory phenotype after spinal cord injury (SCI), what is thought to contribute to secondary tissue degeneration. We previously reported that this is due, in part, to the low levels of anti-inflammatory cytokines, such as IL-4. Since IL-13 and I...

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Detalles Bibliográficos
Autores principales: Amo-Aparicio, Jesus, Garcia-Garcia, Joana, Francos-Quijorna, Isaac, Urpi, Andrea, Esteve-Codina, Anna, Gut, Marta, Quintana, Albert, Lopez-Vales, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581417/
https://www.ncbi.nlm.nih.gov/pubmed/34815787
http://dx.doi.org/10.7150/thno.65203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581417/
https://www.ncbi.nlm.nih.gov/pubmed/34815787
http://dx.doi.org/10.7150/thno.65203

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