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Exosome-mediated delivery of inflammation-responsive Il-10 mRNA for controlled atherosclerosis treatment

Rationale: Tailored inflammation control is badly needed for the treatment of kinds of inflammatory diseases, such as atherosclerosis. IL-10 is a potent anti-inflammatory cytokine, while systemic and repeated delivery could cause detrimental side-effects due to immune repression. In this study, we h...

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Detalles Bibliográficos
Autores principales: Bu, Te, Li, Zhelong, Hou, Ying, Sun, Wenqi, Zhang, Rongxin, Zhao, Lianbi, Wei, Mengying, Yang, Guodong, Yuan, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581418/
https://www.ncbi.nlm.nih.gov/pubmed/34815799
http://dx.doi.org/10.7150/thno.64229