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Peptide ligands targeting FGF receptors promote recovery from dorsal root crush injury via AKT/mTOR signaling

Background: Fibroblast growth factor receptors (FGFRs) are key targets for nerve regeneration and repair. The therapeutic effect of exogenous recombinant FGFs in vivo is limited due to their high molecular weight. Small peptides with low molecular weight, easy diffusion, low immunogenicity, and nont...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Wang, Qiang, Xie, Chen, Cai, Yuling, Chen, Xue, Hou, Yuhui, He, Liu, Li, Jianping, Yao, Min, Chen, Shuangxi, Wu, Wutian, Chen, Xiaojia, Hong, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581430/
https://www.ncbi.nlm.nih.gov/pubmed/34815808
http://dx.doi.org/10.7150/thno.62525