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CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice

Rationale: Platelets play an essential role in atherosclerosis, but the underlying mechanisms remain to be addressed. This study is to investigate the role of platelets in d-flow induced vascular inflammation and the underlying mechanism. Methods: We established a disturbed blood flow (d-flow) model...

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Detalles Bibliográficos
Autores principales: Tang, Chaojun, Wang, Lei, Sheng, Yulan, Zheng, Zhong, Xie, Zhanli, Wu, Fan, You, Tao, Ren, Lijie, Xia, Lijun, Ruan, Changgeng, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581433/
https://www.ncbi.nlm.nih.gov/pubmed/34815786
http://dx.doi.org/10.7150/thno.64601