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Heterogeneity of cell composition and origin identified by single-cell transcriptomics in renal cysts of patients with autosomal dominant polycystic kidney disease

Rationale: Renal cysts in patients with autosomal dominant polycystic kidney disease (ADPKD) can originate from any nephron segments, including proximal tubules (PT), the loop of Henle (LOH), distal tubules (DT), and collecting ducts (CD). Previous studies mostly used limited cell markers and failed...

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Detalles Bibliográficos
Autores principales: Li, Qiong, Wang, Yuchen, Deng, Wenfeng, Liu, Yanna, Geng, Jian, Yan, Ziyan, Li, Fei, Chen, Binshen, Li, Zhuolin, Xia, Renfei, Zeng, Wenli, Liu, Rumin, Xu, Jian, Xiong, Fu, Wu, Chin-Lee, Miao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581434/
https://www.ncbi.nlm.nih.gov/pubmed/34815804
http://dx.doi.org/10.7150/thno.57220