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Biological relevance of Granzymes A and K during E. coli sepsis

Aims: Recent in vitro findings suggest that the serine protease Granzyme K (GzmK) may act as a proinflammatory mediator. However, its role in sepsis is unknown. Here we aim to understand the role of GzmK in a mouse model of bacterial sepsis and compare it to the biological relevance of Granzyme A (G...

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Detalles Bibliográficos
Autores principales: Uranga-Murillo, Iratxe, Tapia, Elena, Garzón-Tituaña, Marcela, Ramirez-Labrada, Ariel, Santiago, Llipsy, Pesini, Cecilia, Esteban, Patricia, Roig, Francisco J, Galvez, Eva M, Bird, Phillip I, Pardo, Julián, Arias, Maykel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581435/
https://www.ncbi.nlm.nih.gov/pubmed/34815792
http://dx.doi.org/10.7150/thno.59418