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Exploring Refinement Strategies for Single Housing of Male C57BL/6JRj Mice: Effect of Cage Divider on Stress-Related Behavior and Hypothalamic-Pituitary-Adrenal-Axis Activity

Introduction: Single housing of laboratory mice is a common practice to meet experimental needs, or to avoid intermale aggression. However, single housing is considered to negatively affect animal welfare and may compromise the scientific validity of experiments. The aim of this study was to investi...

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Detalles Bibliográficos
Autores principales: Buckinx, An, Van Schuerbeek, Andries, Bossuyt, Jo, Allaoui, Wissal, Van Den Herrewegen, Yana, Smolders, Ilse, De Bundel, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581484/
https://www.ncbi.nlm.nih.gov/pubmed/34776890
http://dx.doi.org/10.3389/fnbeh.2021.743959