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Exploring Refinement Strategies for Single Housing of Male C57BL/6JRj Mice: Effect of Cage Divider on Stress-Related Behavior and Hypothalamic-Pituitary-Adrenal-Axis Activity
Introduction: Single housing of laboratory mice is a common practice to meet experimental needs, or to avoid intermale aggression. However, single housing is considered to negatively affect animal welfare and may compromise the scientific validity of experiments. The aim of this study was to investi...
Autores principales: | Buckinx, An, Van Schuerbeek, Andries, Bossuyt, Jo, Allaoui, Wissal, Van Den Herrewegen, Yana, Smolders, Ilse, De Bundel, Dimitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581484/ https://www.ncbi.nlm.nih.gov/pubmed/34776890 http://dx.doi.org/10.3389/fnbeh.2021.743959 |
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