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Depletion of cardiac cardiolipin synthase alters systolic and diastolic function

Cardiolipin (CL) is a major cardiac mitochondrial phospholipid maintaining regular mitochondrial morphology and function in cardiomyocytes. Cardiac CL production includes its biosynthesis and a CL remodeling process. Here we studied the impact of CL biosynthesis and the enzyme cardiolipin synthase (...

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Detalles Bibliográficos
Autores principales: Smeir, Elia, Leberer, Sarah, Blumrich, Annelie, Vogler, Georg, Vasiliades, Anastasia, Dresen, Sandra, Jaeger, Carsten, Gloaguen, Yoann, Klose, Christian, Beule, Dieter, Schulze, P. Christian, Bodmer, Rolf, Foryst-Ludwig, Anna, Kintscher, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581512/
https://www.ncbi.nlm.nih.gov/pubmed/34805785
http://dx.doi.org/10.1016/j.isci.2021.103314