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Depletion of cardiac cardiolipin synthase alters systolic and diastolic function
Cardiolipin (CL) is a major cardiac mitochondrial phospholipid maintaining regular mitochondrial morphology and function in cardiomyocytes. Cardiac CL production includes its biosynthesis and a CL remodeling process. Here we studied the impact of CL biosynthesis and the enzyme cardiolipin synthase (...
Autores principales: | Smeir, Elia, Leberer, Sarah, Blumrich, Annelie, Vogler, Georg, Vasiliades, Anastasia, Dresen, Sandra, Jaeger, Carsten, Gloaguen, Yoann, Klose, Christian, Beule, Dieter, Schulze, P. Christian, Bodmer, Rolf, Foryst-Ludwig, Anna, Kintscher, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581512/ https://www.ncbi.nlm.nih.gov/pubmed/34805785 http://dx.doi.org/10.1016/j.isci.2021.103314 |
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