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In Vitro Activity of Auranofin in Combination With Aztreonam-Avibactam Against Metallo-β-lactamase (MBL)-Producing Enterobacterales

OBJECTIVES: To assess the efficacy of aztreonam-avibactam-auranofin (ATM-AVI-AUR) against a collection of 88 carbapenemase-producing Enterobacterales (CPE) clinical isolates and 6 in vitro selected ATM-AVI-resistant CPE with CMY-16 Tyr150Ser and Asn346His mutants or transformants. METHODS: MICs of i...

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Detalles Bibliográficos
Autores principales: Wang, Wen, Huang, Shifeng, Zou, Chunhong, Ding, Yanhui, Wang, Huijuan, Pu, Shuli, Liao, Yunfeng, Du, Hong, Wang, Deqiang, Chen, Liang, Niu, Siqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581557/
https://www.ncbi.nlm.nih.gov/pubmed/34778107
http://dx.doi.org/10.3389/fcimb.2021.755763