Modulation of adenosine A2a receptor oligomerization by receptor activation and PIP(2) interactions

GPCRs have been shown to form oligomers, which generate distinctive signaling outcomes. However, the structural nature of the oligomerization process remains uncertain. We have characterized oligomeric configurations of the adenosine A2a receptor (A2aR) by combining large-scale molecular dynamics si...

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Detalles Bibliográficos
Autores principales: Song, Wanling, Duncan, Anna L., Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Theory
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581623/
https://www.ncbi.nlm.nih.gov/pubmed/34270937
http://dx.doi.org/10.1016/j.str.2021.06.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581623/
https://www.ncbi.nlm.nih.gov/pubmed/34270937
http://dx.doi.org/10.1016/j.str.2021.06.015

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