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Modulation of adenosine A2a receptor oligomerization by receptor activation and PIP(2) interactions
GPCRs have been shown to form oligomers, which generate distinctive signaling outcomes. However, the structural nature of the oligomerization process remains uncertain. We have characterized oligomeric configurations of the adenosine A2a receptor (A2aR) by combining large-scale molecular dynamics si...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581623/ https://www.ncbi.nlm.nih.gov/pubmed/34270937 http://dx.doi.org/10.1016/j.str.2021.06.015 |