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Characterization of Leader Processing Shows That Partially Processed Mersacidin Is Activated by AprE After Export

The ribosomally synthesized and post-translationally modified peptide mersacidin is a class II lanthipeptide with good activity against Gram-positive bacteria. The intramolecular lanthionine rings, that give mersacidin its stability and antimicrobial activity, are specific structures with potential...

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Detalles Bibliográficos
Autores principales: Viel, Jakob H., van Tilburg, Amanda Y., Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581636/
https://www.ncbi.nlm.nih.gov/pubmed/34777321
http://dx.doi.org/10.3389/fmicb.2021.765659