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Genomic Insights into Myasthenia Gravis Identify Distinct Immunological Mechanisms in Early and Late Onset Disease

OBJECTIVE: The purpose of this study was to identify disease relevant genes and explore underlying immunological mechanisms that contribute to early and late onset forms of myasthenia gravis. METHODS: We used a novel genomic methodology to integrate genomewide association study (GWAS) findings in my...

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Detalles Bibliográficos
Autores principales: Handunnetthi, Lahiru, Knezevic, Bogdan, Kasela, Silva, Burnham, Katie L., Milani, Lili, Irani, Sarosh R., Fang, Hai, Knight, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581766/
https://www.ncbi.nlm.nih.gov/pubmed/34279044
http://dx.doi.org/10.1002/ana.26169