Single Nucleotide Resolution RNA–Protein Cross-Linking Mass Spectrometry: A Simple Extension of the CLIR-MS Workflow

[Image: see text] RNA–protein interactions mediate many intracellular processes. CLIR-MS (cross-linking of isotope-labeled RNA and tandem mass spectrometry) allows the identification of RNA–protein interaction sites at single nucleotide/amino acid resolution in a single experiment. Using isotopicall...

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Detalles Bibliográficos
Autores principales: Götze, Michael, Sarnowski, Chris P., de Vries, Tebbe, Knörlein, Anna, Allain, Frédéric H.-T., Hall, Jonathan, Aebersold, Ruedi, Leitner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581962/
https://www.ncbi.nlm.nih.gov/pubmed/34714631
http://dx.doi.org/10.1021/acs.analchem.1c02384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581962/
https://www.ncbi.nlm.nih.gov/pubmed/34714631
http://dx.doi.org/10.1021/acs.analchem.1c02384

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