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Single Nucleotide Resolution RNA–Protein Cross-Linking Mass Spectrometry: A Simple Extension of the CLIR-MS Workflow

[Image: see text] RNA–protein interactions mediate many intracellular processes. CLIR-MS (cross-linking of isotope-labeled RNA and tandem mass spectrometry) allows the identification of RNA–protein interaction sites at single nucleotide/amino acid resolution in a single experiment. Using isotopicall...

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Detalles Bibliográficos
Autores principales:	Götze, Michael, Sarnowski, Chris P., de Vries, Tebbe, Knörlein, Anna, Allain, Frédéric H.-T., Hall, Jonathan, Aebersold, Ruedi, Leitner, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581962/ https://www.ncbi.nlm.nih.gov/pubmed/34714631 http://dx.doi.org/10.1021/acs.analchem.1c02384

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