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ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) comprises at least two main biologically distinct entities: germinal center B-cell (GCB) and activated B-cell (ABC) subtype. Albeit sharing common lesions, GCB and ABC DLBCL present subtype-specific oncogenic pathway perturbations. ABC DLBCL is typic...

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Detalles Bibliográficos
Autores principales: Sartori, Giulio, Napoli, Sara, Cascione, Luciano, Chung, Elaine Yee Lin, Priebe, Valdemar, Arribas, Alberto Jesus, Mensah, Afua Adjeiwaa, Dall’Angelo, Michela, Falzarano, Chiara, Barnabei, Laura, Forcato, Mattia, Rinaldi, Andrea, Bicciato, Silvio, Thome, Margot, Bertoni, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582153/
https://www.ncbi.nlm.nih.gov/pubmed/34763718
http://dx.doi.org/10.1186/s13046-021-02159-3