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Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma

Aurora A kinase is a cell cycle regulator that is dysregulated in several different malignancies. Nevertheless, its regulatory mechanisms are still not fully understood. Here, we report that ubiquitin specific peptidase 3 (USP3) promotes proliferation and metastasis of esophageal squamous cell carci...

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Detalles Bibliográficos
Autores principales: Shi, Ke, Zhang, Jin Zhong, Yang, Liang, Li, Ning-Ning, Yue, Ying, Du, Xiu-Hong, Zhang, Xiu-Zhi, Lu, Yu Cheng, Guo, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582154/
https://www.ncbi.nlm.nih.gov/pubmed/34758762
http://dx.doi.org/10.1186/s12885-021-08934-x