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Hiding in the dark: pan-cancer characterization of expression and clinical relevance of CD40 to immune checkpoint blockade therapy

CD40 expression correlates with the type I anti-tumor response and better survival. Pan-cancer bioinformatics characterization reveals reduced CD40 expression in 11 cancer types, including RAS(mut) melanoma compared to nevi. RAS mutation correlates with reduced CD40 expression in malignant melanoma....

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Detalles Bibliográficos
Autores principales: Yan, Chi, Richmond, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582157/
https://www.ncbi.nlm.nih.gov/pubmed/34758832
http://dx.doi.org/10.1186/s12943-021-01442-3