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Hiding in the dark: pan-cancer characterization of expression and clinical relevance of CD40 to immune checkpoint blockade therapy
CD40 expression correlates with the type I anti-tumor response and better survival. Pan-cancer bioinformatics characterization reveals reduced CD40 expression in 11 cancer types, including RAS(mut) melanoma compared to nevi. RAS mutation correlates with reduced CD40 expression in malignant melanoma....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582157/ https://www.ncbi.nlm.nih.gov/pubmed/34758832 http://dx.doi.org/10.1186/s12943-021-01442-3 |