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Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends

Physiologically-based pharmacokinetics (PBPK) modeling is a robust tool that supports drug development and the pharmaceutical industry and regulatory authorities. Implementation of predictive systems in the clinics is more than ever a reality, resulting in a surge of interest for PBPK models by clin...

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Detalles Bibliográficos
Autores principales: Abouir, Kenza, Samer, Caroline F, Gloor, Yvonne, Desmeules, Jules A, Daali, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582169/
https://www.ncbi.nlm.nih.gov/pubmed/34776945
http://dx.doi.org/10.3389/fphar.2021.708299