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A fiber-deprived diet causes cognitive impairment and hippocampal microglia-mediated synaptic loss through the gut microbiota and metabolites

BACKGROUND: Cognitive impairment, an increasing mental health issue, is a core feature of the aging brain and neurodegenerative diseases. Industrialized nations especially, have experienced a marked decrease in dietary fiber intake, but the potential mechanism linking low fiber intake and cognitive...

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Detalles Bibliográficos
Autores principales: Shi, Hongli, Ge, Xing, Ma, Xi, Zheng, Mingxuan, Cui, Xiaoying, Pan, Wei, Zheng, Peng, Yang, Xiaoying, Zhang, Peng, Hu, Minmin, Hu, Tao, Tang, Renxian, Zheng, Kuiyang, Huang, Xu-Feng, Yu, Yinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582174/
https://www.ncbi.nlm.nih.gov/pubmed/34758889
http://dx.doi.org/10.1186/s40168-021-01172-0