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Lactate induces aberration in the miR-30a–DBF4 axis to promote the development of gastric cancer and weakens the sensitivity to 5-Fu

BACKGROUND: Gastric cancer (GC) is one of the most common malignancies, molecular mechanism of which is still not clear. Aberrant expression of tumor-associated genes is the major cause of tumorigenesis. DBF4 is an important factor in cancers, although there is yet no report on its function and mole...

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Detalles Bibliográficos
Autores principales: Wang, Tengkai, Ji, Rui, Liu, Guanqun, Ma, Beilei, Wang, Zehua, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582204/
https://www.ncbi.nlm.nih.gov/pubmed/34758839
http://dx.doi.org/10.1186/s12935-021-02291-2