Benzannulation and Hydrocarboxylation Methods for the Synthesis of a Neopentylene-Fused Analogue of Ibuprofen

[Image: see text] Neopentylene ring fusions (ring-fused 4,4-dimethylcyclopentane polycycles) are found in many natural products, but they are largely absent from synthetic compound libraries and focused medicinal chemistry research. Here is reported a synthetic approach to one of the few non-natural...

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Detalles Bibliográficos
Autores principales: Martin, A. C., Rogers, Jessica A., Batsomboon, Paratchata, Morrison, Alec E., Ramsubhag, Ron R., Popp, Brian V., Dudley, Gregory B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582271/
https://www.ncbi.nlm.nih.gov/pubmed/34778682
http://dx.doi.org/10.1021/acsomega.1c04943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582271/
https://www.ncbi.nlm.nih.gov/pubmed/34778682
http://dx.doi.org/10.1021/acsomega.1c04943

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