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Atorvastatin does not ameliorate nephrogenic diabetes insipidus induced by lithium or potassium depletion in mice

Acquired forms of nephrogenic diabetes insipidus (NDI) include lithium (Li)‐induced and hypokalemia‐induced NDI. Both forms are associated with AQP2 downregulation and collecting duct (CD) cellular remodeling. Statins are cholesterol‐lowering drugs appearing to increase AQP2 membrane‐translocation a...

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Detalles Bibliográficos
Autores principales: Thomsen, Maria L., Grønkjær, Camilla, Iervolino, Anna, Rej, Soham, Trepiccione, Francesco, Christensen, Birgitte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582289/
https://www.ncbi.nlm.nih.gov/pubmed/34762363
http://dx.doi.org/10.14814/phy2.15111