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Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

Concomitant with developing pulmonary hypertension (PH), newborn piglets exposed to chronic hypoxia develop pulmonary vascular NO signaling impairments. PH is reduced and NO signaling is improved in chronically hypoxic piglets treated with the NO‐arginine precursor, L‐citrulline. Folic acid positive...

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Detalles Bibliográficos
Autores principales: Douglass, Matthew, Dikalova, Anna, Kaplowitz, Mark R., Zhang, Yongmei, Cunningham, Gary, Summar, Marshall, Fike, Candice D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582293/
https://www.ncbi.nlm.nih.gov/pubmed/34762361
http://dx.doi.org/10.14814/phy2.15096