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Sulfatase-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway

SIMPLE SUMMARY: Liver fibrosis and/or cirrhosis is a major risk factor for hepatocellular carcinoma. Hepatic Fibrogenesis is the result of an excessive production and deposition of extracellular matrix by hepatic myofibroblasts, which are primarily formed from hepatic stellate cells. The heparan sul...

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Detalles Bibliográficos
Autores principales: Nakamura, Ikuo, Asumda, Faizal Z., Moser, Catherine D., Kang, Yoo Na N., Lai, Jin-Ping, Roberts, Lewis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582359/
https://www.ncbi.nlm.nih.gov/pubmed/34771445
http://dx.doi.org/10.3390/cancers13215279