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Emerging Bone Marrow Microenvironment-Driven Mechanisms of Drug Resistance in Acute Myeloid Leukemia: Tangle or Chance?

SIMPLE SUMMARY: Despite high rates of remission obtained with conventional chemotherapy, the persistence of leukemic cells after treatments, eventually exiting in disease relapse, remains the main challenge in acute myeloid leukemia (AML). Increasing evidence indicates that, besides AML cell mutatio...

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Detalles Bibliográficos
Autores principales: Ciciarello, Marilena, Corradi, Giulia, Forte, Dorian, Cavo, Michele, Curti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582363/
https://www.ncbi.nlm.nih.gov/pubmed/34771483
http://dx.doi.org/10.3390/cancers13215319