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CBFB Break-Apart FISH Testing: An Analysis of 1629 AML Cases with a Focus on Atypical Findings and Their Implications in Clinical Diagnosis and Management

SIMPLE SUMMARY: The inv(16)/t(16;16) AML is a disease that is considered relatively easy and straightforward to be diagnosed in the clinical laboratories. Up to date, CBFB FISH and/or CBFB-MYH11 RT-PCR are still the major diagnostic assays utilized in the clinical laboratories. However, incidental C...

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Detalles Bibliográficos
Autores principales: Yang, Richard K., Toruner, Gokce A., Wang, Wei, Fang, Hong, Issa, Ghayas C., Wang, Lulu, Quesada, Andrés E., Thakral, Beenu, Patel, Keyur P., Peng, Guang, Liu, Shujuan, Yin, C. Cameron, Borthakur, Gautam, Tang, Zhenya, Wang, Sa A., Miranda, Roberto N., Khoury, Joseph D., Medeiros, L. Jeffrey, Tang, Guilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582369/
https://www.ncbi.nlm.nih.gov/pubmed/34771519
http://dx.doi.org/10.3390/cancers13215354