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Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells

SIMPLE SUMMARY: Interferon signaling is mostly studied in the context of immune cells. However, its role in glioma cancer cells is unclear. This study aimed to investigate the role of cancer-cell-intrinsic IFN signaling in tumorigenesis in glioblastoma (GBM). We found that GSCs and GBM tumors exhibi...

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Detalles Bibliográficos
Autores principales: Khan, Sabbir, Mahalingam, Rajasekaran, Sen, Shayak, Martinez-Ledesma, Emmanuel, Khan, Arshad, Gandy, Kaitlin, Lang, Frederick F., Sulman, Erik P., Alfaro-Munoz, Kristin D., Majd, Nazanin K., Balasubramaniyan, Veerakumar, de Groot, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582372/
https://www.ncbi.nlm.nih.gov/pubmed/34771447
http://dx.doi.org/10.3390/cancers13215284