CSF1R Inhibition Combined with GM-CSF Reprograms Macrophages and Disrupts Protumoral Interplays with AML Cells

SIMPLE SUMMARY: Acute myeloid leukemia is a blood disease whose long-term treatment is not satisfactory due to frequent (>50%) relapse despite complete initial remission. By adopting protumoral properties, macrophages in the leukemia cell microenvironment may promote resistance to treatment leadi...

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Detalles Bibliográficos
Autores principales: Smirnova, Tatiana, Spertini, Caroline, Spertini, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582394/
https://www.ncbi.nlm.nih.gov/pubmed/34771453
http://dx.doi.org/10.3390/cancers13215289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582394/
https://www.ncbi.nlm.nih.gov/pubmed/34771453
http://dx.doi.org/10.3390/cancers13215289

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