REV1 Inhibition Enhances Radioresistance and Autophagy

SIMPLE SUMMARY: Cancer resistance to therapy continues to be the biggest challenge in treating patients. Targeting the mutagenic translesion synthesis (TLS) polymerase REV1 was previously shown to sensitize cancer cells to chemotherapy. In this study, we tested the ability of REV1 inhibitors to radi...

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Detalles Bibliográficos
Autores principales: Ikeh, Kanayo E., Lamkin, Erica N., Crompton, Andrew, Deutsch, Jamie, Fisher, Kira J., Gray, Mark, Argyle, David J., Lim, Won Y., Korzhnev, Dmitry M., Hadden, M. Kyle, Hong, Jiyong, Zhou, Pei, Chatterjee, Nimrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582445/
https://www.ncbi.nlm.nih.gov/pubmed/34771454
http://dx.doi.org/10.3390/cancers13215290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582445/
https://www.ncbi.nlm.nih.gov/pubmed/34771454
http://dx.doi.org/10.3390/cancers13215290

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