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Implications of TGFβ Signaling and CDK Inhibition for the Treatment of Breast Cancer

SIMPLE SUMMARY: Small molecules that inhibit cyclin dependent kinases (CDKs) have great potential for the treatment of breast cancer and have been implemented in the standard of care for some patients with metastatic disease. As the indications for CDK inhibitors continue to expand, and it is crucia...

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Detalles Bibliográficos
Autores principales: Decker, Joseph T., Ma, Jeffrey A., Shea, Lonnie D., Jeruss, Jacqueline S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582459/
https://www.ncbi.nlm.nih.gov/pubmed/34771508
http://dx.doi.org/10.3390/cancers13215343