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The Cancer-Associated Antigens Sialyl Lewis(a/x) and Sd(a): Two Opposite Faces of Terminal Glycosylation

SIMPLE SUMMARY: The glycosyltransferase β1,4-N-acetylgalactosaminyltransferae 2 (B4GALNT2), product of the B4GALNT2 gene is responsible for the biosynthesis of the carbohydrate antigen Sd(a). Both the enzyme and its cognate antigen display a restricted pattern of tissue expression and modulation in...

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Detalles Bibliográficos
Autores principales: Dall’Olio, Fabio, Pucci, Michela, Malagolini, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582462/
https://www.ncbi.nlm.nih.gov/pubmed/34771437
http://dx.doi.org/10.3390/cancers13215273