CD95L Inhibition Impacts Gemcitabine-Mediated Effects and Non-Apoptotic Signaling of TNF-α and TRAIL in Pancreatic Tumor Cells

SIMPLE SUMMARY: Death receptors may induce cellular death upon ligand binding but also activate other pro-inflammatory mechanisms in cancer cells, which may increase malignancy. The transcription factor NFkB works as a central hub in this system and connects the signaling of three major death ligand...

Descripción completa

Detalles Bibliográficos
Autores principales: Rashid, Khalid, Röder, Christian, Goumas, Freya, Egberts, Jan-Hendrik, Kalthoff, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582466/
https://www.ncbi.nlm.nih.gov/pubmed/34771621
http://dx.doi.org/10.3390/cancers13215458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582466/
https://www.ncbi.nlm.nih.gov/pubmed/34771621
http://dx.doi.org/10.3390/cancers13215458

Ejemplares similares