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CD95L Inhibition Impacts Gemcitabine-Mediated Effects and Non-Apoptotic Signaling of TNF-α and TRAIL in Pancreatic Tumor Cells

SIMPLE SUMMARY: Death receptors may induce cellular death upon ligand binding but also activate other pro-inflammatory mechanisms in cancer cells, which may increase malignancy. The transcription factor NFkB works as a central hub in this system and connects the signaling of three major death ligand...

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Detalles Bibliográficos
Autores principales:	Rashid, Khalid, Röder, Christian, Goumas, Freya, Egberts, Jan-Hendrik, Kalthoff, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582466/ https://www.ncbi.nlm.nih.gov/pubmed/34771621 http://dx.doi.org/10.3390/cancers13215458

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