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Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells

SIMPLE SUMMARY: Lung cancer is strongly associated with tobacco smoking. Nicotine in tobacco smoke can be transformed into a carcinogen after in vivo metabolism. However, the mechanism of how nicotine metabolites modulate a pro-tumorigenic microenvironment remains largely unknown. We have explored t...

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Detalles Bibliográficos
Autores principales: Kwok, Hoi-Hin, Gao, Boning, Chan, Koon-Ho, Ip, Mary Sau-Man, Minna, John Dorrance, Lam, David Chi-Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582493/
https://www.ncbi.nlm.nih.gov/pubmed/34771509
http://dx.doi.org/10.3390/cancers13215345