Somatic Hypomethylation of Pericentromeric SST1 Repeats and Tetraploidization in Human Colorectal Cancer Cells

SIMPLE SUMMARY: Cancer cells frequently exhibit an abnormal number of chromosomes, termed aneuploidy, often preceded by an aberrant genome duplication resulting in cells with double the number of chromosomes (tetraploidy). The cause of the aberrant genome-doubling remains unknown. Loss of DNA methyl...

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Detalles Bibliográficos
Autores principales: González, Beatriz, Navarro-Jiménez, Maria, Alonso-De Gennaro, María José, Jansen, Sanne Marcia, Granada, Isabel, Perucho, Manuel, Alonso, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582499/
https://www.ncbi.nlm.nih.gov/pubmed/34771515
http://dx.doi.org/10.3390/cancers13215353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582499/
https://www.ncbi.nlm.nih.gov/pubmed/34771515
http://dx.doi.org/10.3390/cancers13215353

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