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Somatic Hypomethylation of Pericentromeric SST1 Repeats and Tetraploidization in Human Colorectal Cancer Cells
SIMPLE SUMMARY: Cancer cells frequently exhibit an abnormal number of chromosomes, termed aneuploidy, often preceded by an aberrant genome duplication resulting in cells with double the number of chromosomes (tetraploidy). The cause of the aberrant genome-doubling remains unknown. Loss of DNA methyl...
Autores principales: | González, Beatriz, Navarro-Jiménez, Maria, Alonso-De Gennaro, María José, Jansen, Sanne Marcia, Granada, Isabel, Perucho, Manuel, Alonso, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582499/ https://www.ncbi.nlm.nih.gov/pubmed/34771515 http://dx.doi.org/10.3390/cancers13215353 |
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