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Disruption of Tumor Suppressors HNF4α/HNF1α Causes Tumorigenesis in Liver
SIMPLE SUMMARY: Liver cancer is one of the deadliest human cancers. High-throughput analysis of cancer cell genomes has established that hotspot mutations in HNF4α and HNF1α occur in a variety of human cancers, including liver cancer. Here, we review recent findings pertaining to role of HNF1α and H...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582545/ https://www.ncbi.nlm.nih.gov/pubmed/34771521 http://dx.doi.org/10.3390/cancers13215357 |