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Disruption of Tumor Suppressors HNF4α/HNF1α Causes Tumorigenesis in Liver

SIMPLE SUMMARY: Liver cancer is one of the deadliest human cancers. High-throughput analysis of cancer cell genomes has established that hotspot mutations in HNF4α and HNF1α occur in a variety of human cancers, including liver cancer. Here, we review recent findings pertaining to role of HNF1α and H...

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Detalles Bibliográficos
Autores principales: Teeli, Aamir Salam, Łuczyńska, Kamila, Haque, Effi, Gayas, Mohmmad Abrar, Winiarczyk, Dawid, Taniguchi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582545/
https://www.ncbi.nlm.nih.gov/pubmed/34771521
http://dx.doi.org/10.3390/cancers13215357