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NTRK1/TrkA Signaling in Neuroblastoma Cells Induces Nuclear Reorganization and Intra-Nuclear Aggregation of Lamin A/C

SIMPLE SUMMARY: Neuroblastoma (NB) accounts for 15% of all cancer-related deaths of children. While the amplification of the Myc-N proto-oncogene (MYCN) is a major driver of aggressive NB, the expression of the neurotrophin receptor, NTRK1/TrkA, has been shown to be associated with an excellent outc...

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Detalles Bibliográficos
Autores principales: Funke, Lukas, Bracht, Thilo, Oeck, Sebastian, Schork, Karin, Stepath, Markus, Dreesmann, Sabine, Eisenacher, Martin, Sitek, Barbara, Schramm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582546/
https://www.ncbi.nlm.nih.gov/pubmed/34771457
http://dx.doi.org/10.3390/cancers13215293